PeptideAtlas

The PeptideAtlas project, at the Institute of Systems Biology (ISB, Seattle, USA), annotates genome sequences of different organisms with peptides and proteins derived mainly from MS/MS data. It is very important to highlight here that prior to storage all data in PeptideAtlas is reprocessed, in this case via the popular Trans Proteomics Pipeline (TPP). The identified sequences are then mapped onto their respective genome sequence, resulting into species or sample-specific ‘builds’, which represent all peptides mapped to a single reference Ensembl genome. As a matter of fact, PeptideAtlas is a peptide centric repository and aims to reprocess periodically the available data with new tools for identification and statistical validation, therefore providing an up to date vision of a particular proteome.